Virtual Target Screening: Validation Using Kinase Inhibitors
نویسندگان
چکیده
منابع مشابه
Virtual Target Screening: Validation Using Kinase Inhibitors
Computational methods involving virtual screening could potentially be employed to discover new biomolecular targets for an individual molecule of interest (MOI). However, existing scoring functions may not accurately differentiate proteins to which the MOI binds from a larger set of macromolecules in a protein structural database. An MOI will most likely have varying degrees of predicted bindi...
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ژورنال
عنوان ژورنال: Journal of Chemical Information and Modeling
سال: 2012
ISSN: 1549-9596,1549-960X
DOI: 10.1021/ci300073m